FROM THE PHARMACY

THE MEDICAINE BLOG

Protocol, compounding law, and safety — written for the provider holding the jar, not for a search engine. Every post is reviewed by the compounding pharmacy that makes the product.

Compounding & Compliance

503A vs 503B: What It Means for the Numbing Cream You Buy

Two different legal lanes produce two very different products. One explains why your numbing cream can be a 20/10/10 triple-anesthetic compound; the other explains why a distributor can sell you a case off a shelf. Knowing which you are buying from changes what you can expect on strength, consistency, and paperwork.

September 17, 2026 8 min read

Protocol

How Long to Leave Numbing Cream On: Dwell Time and Occlusion by Procedure

The single most common reason a strong compound underperforms is not the formula — it is twelve minutes of dwell time and no occlusion. Here is what the cream is actually doing while it sits, and the timing that matches each procedure.

September 17, 2026 9 min read

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