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MediCaine compound numbing cream brand markMEDICAINE
BOTOX · DYSPORT · INJECTABLES

NUMBING CREAM FOR BOTOX & INJECTABLE TREATMENTS

Compound BLT for injection comfort before Botox, Dysport, and injectable treatments. Reliable surface numbing that does not distort tissue like infiltrated local. Approximately 15-minute onset, 2 to 4 hours of working time. For licensed providers.

Build Your Order Call (310) 889-0733
WHY BLT FOR INJECTIONS

MATCH THE FORMULA TO THE TREATMENT

A topical anesthetic numbs the surface for the needle stick without adding volume or distorting tissue. Pick the tier that matches your injectable workflow.

TOX · WRINKLE RELAXERS

BOTOX & DYSPORT

Neuromodulator injections for forehead, glabella, crow's feet, and lower face. Triple-agent BLT gives reliable comfort for needle-shy patients. MediCaine Pro applied per protocol is the everyday standard.

Recommended: Pro
SENSITIVE · ALLERGY

BENZOCAINE-FREE

For patients with benzocaine sensitivity, MediCaine Elite (Lidocaine 30% + Tetracaine 7%) delivers high-concentration numbing without benzocaine — useful for reactive or allergy-prone skin.

Recommended: Elite
FILLER · MULTI-AREA

FILLER & LONG SESSIONS

Combining tox with dermal filler or treating multiple zones. For lip and perioral filler, see our lip filler numbing guide. The extended duration of MediCaine Ultra suits longer combination sessions.

Recommended: Pro / Ultra
PROTOCOL

INJECTABLE APPLICATION

  1. 1

    CLEANSE THE TREATMENT ZONE

    Cleanse the area and confirm skin is intact. Follow your own provider protocol for consent, documentation, and injection planning.

  2. 2

    APPLY A THIN LAYER

    Apply a thin, even layer across the injection zone including margins, per protocol. Use the smallest effective amount and stay within labeled dose limits.

  3. 3

    WAIT ABOUT 15 TO 30 MINUTES

    Onset is around 15 minutes on thin facial skin. Allow up to 30 minutes for thicker areas. Working time is 2 to 4 hours depending on tier.

  4. 4

    REMOVE AND PREP

    Wipe the cream off completely, then perform skin antisepsis. Injection sites must be clean and prepped before the needle is introduced.

  5. 5

    INJECT PER TECHNIQUE

    Because topical anesthetic adds no volume, tissue landmarks stay undistorted for precise placement. Proceed with your standard injection technique.

WHY MEDICAINE

COMPOUNDED FOR PROVIDERS

503A

Compounded fresh per order in a 503A pharmacy in the USA — not a mass-produced OTC product.

USP-795

Prepared to USP-795 non-sterile compounding standards for consistent, documented quality.

NPI

Dispensed to licensed providers only, after NPI verification. A provider-use Rx compound — not resold to patients.

WHERE THE DISCOMFORT ACTUALLY IS

A FINE NEEDLE, MANY TIMES

Neurotoxin injections use a very fine needle, and plenty of patients tolerate them with nothing at all. What patients react to is the count: a glabella, forehead and crow's feet pattern can be twenty entry points in a few minutes.

THE NEEDLE-ANXIOUS

For a first-time or needle-anxious patient, numbing the treatment map beforehand is often the difference between a calm appointment and one that never gets rebooked.

SENSITIVE ZONES

The glabella and upper lip are reliably the least comfortable areas to inject. Many practices numb only those and leave the rest.

COMBINED APPOINTMENTS

Toxin booked alongside filler, microneedling or a peel changes the calculus — the session is longer and goes deeper. See lip filler numbing.

FITTING IT INTO THE APPOINTMENT

TOXIN VISITS ARE SHORT

A toxin appointment can run fifteen minutes. A topical that needs an hour under a dressing does not fit that schedule; a ~15-minute onset does.

NUMB AT CHECK-IN

Apply while consent, photographs and the treatment plan are handled. By the time you have drawn up, it is working.

MARK, THEN NUMB

Assess movement and mark your points before anything goes on the skin — removing the cream lifts marker lines.

REMOVE, THEN PREP

Wipe it off completely and run your standard antiseptic prep before the first injection. Nothing should sit between the needle and clean skin.

INTACT SKIN ONLY

Never over broken or irritated skin, and never wrapped or heated while it works. Apply, wait, remove.

FAQ

BOTOX NUMBING QUESTIONS

What is the best numbing cream for Botox and injectables?+
Compound BLT (Benzocaine 20% + Lidocaine 10% + Tetracaine 10%) is the standard pre-injection topical for Botox, Dysport, and most injectables. Onset is ~15 minutes with 2 to 4 hours of working time. For benzocaine sensitivity, MediCaine Elite is benzocaine-free. All tiers are restricted to licensed providers and dispensed after NPI verification.
How long before injectables should numbing cream be applied?+
Apply a thin layer 15 to 30 minutes before injecting, per protocol. On thin facial skin, onset is around 15 minutes. Remove the cream completely and perform skin antisepsis before injecting — the sites must be clean and prepped.
Does numbing cream affect Botox or Dysport results?+
Topical BLT is applied to the skin surface and removed before injection, so it does not dilute or displace neuromodulator product the way injected local with volume can. Many injectors prefer a topical for tox work for this reason. Follow your protocol for timing, antisepsis, and technique.
Can the same numbing cream be used for filler injections?+
Yes. Compound BLT is used ahead of dermal filler as well as neuromodulators. For lip and perioral filler, see our lip filler guide. For multi-area or longer sessions, some injectors step up to Ultra for extended working time.
What is the best numbing cream for Botox?+
For a short toxin appointment, what matters is onset rather than maximum depth: a compounded BLT reaches working depth in about 15 minutes, so it fits inside consent and mapping. MediCaine Pro is the everyday choice; Elite is benzocaine-free for patients who react to benzocaine. Many patients need nothing at all — this is for the ones who do.
How long before Botox should numbing cream be applied?+
As a general guide, roughly 15 to 20 minutes before injecting, on clean, dry, intact skin — then removed completely before antiseptic prep. Mark your injection points first, because wiping the cream away lifts marker lines. Always follow your own clinical protocol.
Do you actually need numbing cream for Botox?+
Often not. The needle is very fine and many patients tolerate a full treatment without it. Practices tend to reach for a topical with needle-anxious or first-time patients, on the glabella and upper lip, or when toxin is combined with filler or another procedure in the same visit.
Does it work the same for Dysport, Xeomin and Jeuveau?+
The topical numbs the skin the needle passes through, so the brand of neurotoxin in the syringe does not change how it is applied. Your injection technique, dilution and placement are unaffected — the cream is removed before you inject.
Can we buy numbing cream for injections online?+
Through this site, yes, if you are a licensed provider. Build the order, we verify your NPI and state licence against the CMS registry, a pharmacist confirms it and sends a secure payment link, and the batch is compounded fresh and shipped in 2–3 business days. It is not sold retail.

PROFESSIONAL INJECTION NUMBING

Compounded fresh per order. Single-use packets or pro jars. License verified before your first shipment.

Build Your Order Call (310) 889-0733
Call to Order · (310) 889-0733